Front Cover Picture: Multigram‐Scale Kinetic Resolution of 4‐Acetyl[2.2]Paracyclophane via Ru‐Catalyzed Enantioselective Hydrogenation: Accessing [2.2]Paracyclophanes with Planar and Central Chirality (Adv. Synth. Catal. 11/2021)

The front cover picture was designed by C. Zippel, Z. Hassan and S. Bräse. Kinetic resolution of 4-acetyl[2.2] paracyclophane via ruthenium-catalyzed enantioselective hydrogenation has been realized. This method can be performed on a multigram-scale gives access to enantiomerically pure derivatives with planar central chirality (Rp)-4-acetyl-PCP (97% ee, 43%) (Sp,S)-PCP 46%), which are useful intermediates since it transformed into wide variety enantiopure for the synthesis PCP-based ligand/catalyst systems chiroptical materials. Details found in Update Stefan Bräse co-workers (C. Hassan, A. Q. Parsa, J. Hohmann, Bräse, Adv. Synth. Catal. 2021, 363, 2861–2865; DOI: 10.1002/adsc.202001536).